Jeffrey Epstein’s mysterious death occurred six years ago this month — but the National Enquirer has discovered 22 people in the sketchy billionaire’s orbit have also died under murky circumstances, fueling fears of a cover-up by powerful figures seeking to erase potential witnesses.

From the predator’s alleged victims to house managers, lawyers, accountants, investigative journalists and pimps, the list of unexplained fatalities traces a dark money trail that leads straight to Epstein’s inner circle, sources say.

Financier Steven Hoffenberg confessed in a final account before his death to the Enquirer’s Doug Montero that Epstein and Ghislaine Maxwell, the convicted pedophile’s now-imprisoned recruiting madam, were “taping” honey-trap videos of sleazy VIPs with underage girls for a cabal of deep-state blackmailing power brokers.

Hoffenberg, the former Towers Financial CEO and Epstein associate — who died in 2022 at 77 after serving 18 years for a $475 million Ponzi scheme — cooperated with the FBI and spoke out about his former protégé’s alleged connections to Israel’s national intelligence agency Mossad.

While Maxwell, 63, is serving 20 years for sex trafficking, Epstein himself became part of the growing body count in August 2019 when he was found hanged inside his New York City jail cell at 66 in what officials deemed a suicide — but his brother, Mark, calls “murder.”

Epstein’s final cellmate, Efrain “Stone” Reyes, 51, died of COVID in November 2020 just weeks after talking with federal investigators probing the monstrous moneyman’s death. Reyes was transferred out of Epstein’s cell just one day before the bigwig’s death, per Daily Mail.