A breakthrough mRNA cancer vaccine has shown the ability to supercharge the effects of immunotherapy in mice, sparking hope for a universal “off-the-shelf” treatment that could fight multiple cancers. Unlike traditional vaccines designed to target specific tumor proteins, this approach simply revs up the immune system as if it were fighting a virus. The results were dramatic—when paired with checkpoint inhibitors, tumors shrank, and in some cases, the vaccine alone wiped them out.
mRNA!? We don’t take kindly to mRNA in these parts. We like our bodies like our religion. Cancerous!
Cancer vaccines cause autism!!! This will be said by the ignorant goons.
As someone who is not well-versed on the subject, I worry that treatments like this could result in autimmune conditions. Is that an irrational fear? What helps the immune system discriminate between healthy and cancerous cells after this treatment is administered?
May 2022
Autoimmunity and Cancer—Two Sides of the Same Coin
With the current paper, we also aim to convince the readers that the pathways involved in cancer and autoimmune disease development consist of similar molecular players working in opposite directions. Therefore, a deep understanding of the two sides of immune tolerance is crucial for the proper designing of novel and selective immunotherapies.
