I geuss i js want to know from some folks who are on prog rn how do you take it why do you take it that way and what can i expect
i take it rectally because of the justification in this article. taking it orally is pretty much a waste of time unless you really want the high or the sleepiness from taking it orally. i would love to have another option but they pretty much only prescribe pills. apparently you can get an implant which i would love so i have one less thing i have to do every day.
as for how, i put a little glob of surgilube on the pill and just push it into my butt with a finger. i have to take two now but the one glob of lube is usually more than enough. sometimes i get a little bit of fecal matter on my finger if i had a bowel movement that day, but its not a big deal and is easy enough to wash off. i have a bidet so i just use that to wash off any lube on the outside. its weird sometimes ill have a bowel movement and i can see the disintegrated pill casing spread over the stool.
I want to 2nd this. I temporarily took my 300mg of prog orally while recovering from bottom surgery, and all it really did was make me feel a bit more sleepy.
That article and other sources I’ve come across show higher and longer lasting delivery of the medication when taken as a suppository. After I returned to that, I felt better than I did while taking it orally (albeit the surgery recovery may have played a part). I do the same as you, just a small squeeze of water based lube does the trick and I wipe/wash up afterwards. Take it at the end of the day, making sure you don’t poop until after you sleep. The casing is often present for me as well.
Thanks for the reply i will read the articticle later
Well if im reading this correctly oraly will give you a really low dose of prog in ur blood and taking more will make you go bald due to dht conversion
200mg Orally each night. Not super sure about its effectiveness to be honest 🤷♀️ It didn’t affect my libido, and it’s hard for me to quantity how/if it affected my breast growth. What it does do for me is make me sleepy after taking it. Some people might see this as a bad thing, but I honestly like that I have an additional something that helps with sleep (also prescribed Clonidine ER for sleep). I did try rectally for a few weeks; it just wasn’t convenient enough to continue, and I missed the evening sedative effect. I do hope we eventually see some good studies that explore it more in trans context (different routes, timing during transition, impact of age and desired effects, etc).
How long have you been taking it i have heard from some other folks that it takes a few months for the effects to kick in how was / is that for you
Looking back on my prescription history ~ it looks like I was originally prescribed 100mg which I took for around 11 months and then was moved up to 200mg which I’ve been taking for about 6 months… Or something like that! The refill+pickup dates and everything overlap a bit oddly.
Effects-wise… Far too many variables 🤭 I had been on hrt for about 8 months, so any breast growth feels more general than boosted/aided by the prog. Some people report it helps fill there’s out, but I can’t necessarily say it helped me there. I tend to believe my genetics, age, and overall nutrition have a greater impact on how my chest has developed (on the smaller side). Libido has been muted since starting hrt. It did spike for a few weeks a bit after increasing my dose, but there were a lot of social & emotional factors that I feel contributed to that; it has since returned to zero 🤷♀️
I’ve been taking 200mg/day orally for a while but had little effect from it that I can tell. I’ve been considering figuring out a way of using it vaginally. I had peritoneal pull through vaginoplasty, so I’m thinking absorption would be better than penile inversion vagina absorption which has been shown to not be great. I might try rectal if that doesn’t work, but I’m not a fan of that idea. Either way it’s difficult to get the suppositories, so I was thinking of extracting the liquid from the pills and mixing it with a vaginal-safe cream.
Thats quite intresting i belive you can also get creams wich already contain prog where i live so ill also be looking into that
Yeah, I can’t get any with pharmaceutical grade progesterone. Only naturally derived which is completely unregulated in the US, usually extracted from a type of wild yam. I’m not sure how effective that is or what brands actually contain what they say they contain.
I do 100 mg a day rectally because when I was prescribed it, I asked my dr about taking it recally, and he said that yes some gets got by the liver before it can get to the blood stream, but women taking it generally get enough, so I shouldn’t need to worry about going in the other end. I went a week taking it orally, got the worst insomnia of my life, about 8 hours over 6 days according to my watch, so I switched to taking it rectally, and the insomnia disappeared. Last I checked, my levels were normal
Prog is so intresting it nocks some folks out and cooks sleep for others :) well am glad its working better for you now



